Our long-term aim is to shed new light on the complex interrelated networks formed in melanoma, understand how these interactions drive the disease, how they affect response to drug administration and how we can utilize this information to treat melanoma patients.Our strategy involves the application of a multi-faceted approach using our melanoma tumor bank, our established rich genetic database, coupled with novel functional genomics and proteomic techniques, as well as computational tools. The dissection of these interactions holds promise of providing novel melanoma mechanistic insights