My expertise is in immunopharmacology of allergy focusing on mast cells and eosinophils, their activating and inhibitory receptors, their cross-talk for a better prophylaxis/treatment of allergic diseases. My lab studies the role of mast cells and eosinophils in hypoxia (allergy, COPD); mastocytosis and its treatment; the crosstalk between atopic dermatitis and asthma with the microbiome. We are developing novel monoclonal antibodies and bispecific antibodies against activating and inhibiting receptors on mast cells and eosinophils for the treatment of allergy and of selected solid tumors.