We use evolutionary and ecological theories to investigate the interactions between microbes, their vertebrate hosts, arthropod vectors, and the surrounding environment. We address three fundamental questions:
1) Do different mechanisms operate in microbes than in macroorganisms?
2) What are the main selective pressures and their effects on microbial community composition within hosts and vectors?
3) What are the evolutionary and ecological mechanisms that determine the interplay between hosts, vectors, and their pathogenic microbes?