The Harel lab is exploring fundamental questions in aging research, such as why is aging such a strong driver of disease, and what is the molecular basis behind the outstanding diversity in vertebrate lifespan (which can reach up to 1000-fold differences).

To this end, we develop state-of-the-art genome engineering for the naturally short-lived turquoise killifish model, and apply cutting-edge in-vivo imaging, single-cell and computational approaches, as well as disease modeling in mammalian models. Have a look at a video abstract of the lab and our recent studies at http://harel-lab.com/