My research focuses on the discovery and characterization of genes responsible for hereditary hearing loss and neurodevelopmental diseases. My work has covered the transcriptome and epigenome of the auditory and vestibular systems, in order to dissect the regulatory pathways of these systems. My team has studied the mechanisms and pathophysiology of deafness in several mouse models, which mimic human disease. We have created a number of mouse mutants using the gene editing tool CRISPR/Cas9. Moreover, we are using AAV-gene therapy to rescue hearing in mouse models for human deafness.