Our laboratory conducts neuro-Vascular research focused on the molecular and cellular aberrations of the Blood Brain Barrier (BBB) in central nervous system (CNS) pathologies. We also study the differentiation processes of BBB endothelial cells during embryonic development. The function of a blood vessel in the brain is very different than that of peripheral blood vessels. To maintain the brain environment, capillaries must first isolate the brain from the blood, and then, very tightly control, the influx/efflux of materials through the capillary wall. Indeed, the homeostasis is maintained by